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CRC 1335
Aberrant Immune Signals in Cancer

Technische Universität München

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Home » Projects - Overview

P01  |  Jürgen Ruland
Aberrant T cell receptor signaling pathways in lymphoma

P02  | Maike Buchner
Impact of intrinsic and extrinsic immune cell signaling on chronic lymphocytic leukemia

P03  | Ulrich Keller
Aberrant CXCR4 signaling in lymphoma

P04  | Oliver Weigert
Aberrant Cathepsin S activity in follicular lymphoma

P05  | Vanesa Fernández-Sáiz & Marc Schmidt-Supprian
Exploring the pathogenic roles of enhanced c-Rel function in cancer

P06  | Florian Bassermann
Role of SCF-type ubiquitin ligases in NF-κB driven lymphomagenesis

P07  | Daniel Krappmann
Mechanisms and consequences of MALT1 scaffolding and proteolytic activity in ABC DLBCL

P08  | Jürgen Ruland & Barbara Schraml
Mechanisms of inflammatory Card9 signaling in intestinal carcinogenesis

P10  | Philipp Jost
Characterization of aberrant immune signals driven by inflammatory cell death in cancer

Image from "Munkhbaatar, E. (2020). Nat Commun 11"(link is external). CCA 4.0 International License(link is external)

P11  | Dirk Haller
Integration of inflammation and pattern recognition receptor signaling into unfolded protein response-driven colonic tumorigenesis

P12  | Dieter Saur
Inflammatory pathways in subtypes of intestinal cancer

P13  | Roland Rad
Genome-wide in vivo screens for immune signaling components in intestinal cancer

P14  | Hendrik Poeck
Mechanisms of immune evasion caused by aberrant innate nucleic acid receptor signaling in tumor cells and their tumor microenvironment

P15  | Veit Hornung
Tumor-intrinsic vs. microenvironment dependent roles of IL-1 secretion and signaling in melanoma

P16  | Felix Meissner
Dissecting the communication between immune and tumor cells with quantitative proteomics

P17  | Tilo Biedermann
Impact of aberrant immune signaling in melanoma mast cell networks on melanoma progression and metastasis

P18  | Christina Zielinski
Regulation of T cell antitumor immunity by tonicity signals from the tumor microenvironment


Image from "Matthias, J. et al. (2019). Sci Transl Med 11". Reprinted with permission from AAAS.(link is external)

P19  | Mathias Heikenwälder
On the role of adaptive and innate immune-cell receptor signaling in NASH and subsequent liver cancer

Image form "Pfister, D. et al. (2021). Nature 592"(link is external). CCA 4.0 International License(link is external)

Z01  | Katja Steiger & Wilko Weichert
Comparative animal pathology core and tissue cohort outreach

Spokesperson
Prof. Dr. Jürgen Ruland

Office
Dr. Silvia Thöne
Dr. Michael Eitel


Institut für Klinische Chemie und Pathobiochemie
Klinikum rechts der Isar der TUM
Ismaninger Straße 22
81675 München


Phone: +49.89.4140.4758
E-Mail: sfb1335.med@tum.de
Website: www.sfb1335.de

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