Publications



Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.


Rosenberg, N., Van Haele, M., Lanton, T., Brashi, N., Bromberg, Z., Adler, H., Giladi, H., Peled, A., Goldenberg, D. S., Axelrod, J. H., Simerzin, A., Chai, C., Paldor, M., Markezana, A., Yaish, D., Shemulian, Z., Gross, D., Barnoy, S., Gefen, M., Amran, O., Claerhout, S., Fernandez-Vaquero, M., Garcia-Beccaria, M., Heide, D., Shoshkes-Carmel, M., Arras, D. S., Elgavish, S., Nevo, Y., Benyamini, H., Tirnitz-Parker, J. E. E., Sanchez, A., Herrera, B., Safadi, R., Kaestner, K. H., Rose-John, S., Roskams, T., Heikenwalder, M. & Galun, E. (2022). J. Hepatol., 77, 1631-1641.

DOI:10.1016/j.jhep.2022.07.029

Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status


Bader, J. M., Deigendesch, N., Misch, M., Mann, M., Koch, A. & Meissner, F. (2023). Cell Rep Med, 4, 100877.

DOI:10.1016/j.xcrm.2022.100877

Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues.


Probst, H. C., Stoitzner, P., Amon, L., Backer, R. A., Brand, A., Chen, J., Clausen, B. E., Dieckmann, S., Dudziak, D., Heger, L., Hodapp, K., Hornsteiner, F., Hovav, A. H., Jacobi, L., Ji, X., Kamenjarin, N., Lahl, K., Lahmar, I., Lakus, J., Lehmann, C. H. K., Ortner, D., Picard, M., Roberti, M. P., Rossnagel, L., Saba, Y., Schalla, C., Schlitzer, A., Schraml, B. U., Schütze, K., Seichter, A., Seré, K., Seretis, A., Sopper, S., Strandt, H., Sykora, M. M., Theobald, H., Tripp, C. H. & Zitvogel, L. (2022). Eur J Immunol. 0:1-78.

DOI:10.1002/eji.202249819

T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer.


Xue, B., von Heyking, K., Gassmann, H., Poorebrahim, M., Thiede, M., Schober, K., Mautner, J., Hauer, J., Ruland, J., Busch, D. H., Thiel, U. & Burdach, S. E. G. (2022). Cancers (Basel), 14.

DOI:10.3390/cancers14225485

α-Gal present on both glycolipids and glycoproteins contributes to immune response in meat-allergic patients


Chakrapani, N., Fischer, J., Swiontek, K., Codreanu-Morel, F., Hannachi, F., Morisset, M., Mugemana, C., Bulaev, D., Blank, S., Bindslev-Jensen, C., Biedermann, T., Ollert, M. & Hilger, C. (2022). Allergy Clin Immunol, 150, 396-405.e311.

DOI:10.1016/j.jaci.2022.02.030

Combining precision oncology and immunotherapy by targeting the MALT1 protease.


Mempel, T. R., Krappmann, D. (2022). J Immunother Cancer 10.
DOI:10.1136/jitc-2022-005442

The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma


Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J., Klaeger, S., Walzik, M., Öllinger, R., Engleitner, T., Wirth, M., Keller, U., Krönke, J., Rudelius, M., Kossatz, S., Rad, R., Kuster, B., Bassermann, F. (2022). EMBO J 41, e110871.

DOI:10.15252/embj.2022110871

A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.


Kreft, L., Schepers, A., Hils, M., Swiontek, K., Flatley, A., Janowski, R., Mirzaei, M. K., Dittmar, M., Chakrapani, N., Desai, M. S., Eyerich, S., Deng, L., Niessing, D., Fischer, K., Feederle, R., Blank, S., Schmidt-Weber, C. B., Hilger, C., Biedermann, T., Ohnmacht, C. (2022). Front Immunol 13, 958952.

DOI:10.3389/fimmu.2022.958952

Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection


Khatamzas, E., Antwerpen, M. H., Rehn, A., Graf, A., Hellmuth, J. C., Hollaus, A., Mohr, A. W., Gaitzsch, E., Weiglein, T., Georgi, E., Scherer, C., Stecher, S. S., Gruetzner, S., Blum, H., Krebs, S., Reischer, A., Leutbecher, A., Subklewe, M., Dick, A., Zange, S., Girl, P., Müller, K., Weigert, O., Hopfner, K. P., Stemmler, H. J., von Bergwelt-Baildon, M., Keppler, O. T., Wölfel, R., Muenchhoff, M., Moosmann, A. (2022). Nat Commun 13, 5586.

DOI:10.1038/s41467-022-32772-5

Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits


Peiseler, M., Schwabe, R., Hampe, J., Kubes, P., Heikenwälder, M., Tacke, F. (2022). J Hepatol 77, 1136-1160.

DOI:10.1016/j.jhep.2022.06.012