Publications



Vascular Remodeling Is a Crucial Event in the Early Phase of Hepatocarcinogenesis in Rodent Models for Liver Tumorigenesis


Tulessin, M., Sarker, R.S.J., Griger, J., Leibing, T., Geraud, C., Weichert, W., Steiger, K., Mogler, C. (2022). Cells 11.

DOI:10.3390/cells11142129

pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas-proposal for a new pT3a/pT3b subclassification


Foersch, S., Lang-Schwarz, C., Eckstein, M., Geppert, C., Schmitt, M., Konukiewitz, B., Groll, T., Schicktanz, F., Engel, J., Gleitsmann, M., Westhoff, C.C., Frickel, N., Litmeyer, A.S., Grass, A., Jank, P., Lange, S., Tschurtschenthaler, M., Wilhelm, D., Roth, W., Vieth, M., Denkert, C., Nagtegaal, I., Weichert, W., Jesinghaus, M. (2022). Br J Cancer.

DOI:10.1038/s41416-022-01889-1

Optimized CRISPR-Cas9-based Strategy for Complex Gene Targeting in Murine Embryonic Stem Cells for Germline Transmission


O'Neill, T.J., Krappmann, D., Gewies, A. (2022). Bio Protoc 12, e4423.

DOI:10.21769/BioProtoc.4423

Ly6D(+)Siglec-H(+) precursors contribute to conventional dendritic cells via a Zbtb46(+)Ly6D(+) intermediary stage


Lutz, K., Musumeci, A., Sie, C., Dursun, E., Winheim, E., Bagnoli, J., Ziegenhain, C., Rausch, L., Bergen, V., Luecken, M.D., Oostendorp, R.A.J., Schraml, B.U., Theis, F.J., Enard, W., Korn, T., Krug, A.B. (2022). Nat Commun 13, 3456.

DOI:10.1038/s41467-022-31054-4

Ly6D(+)Siglec-H(+) precursors contribute to conventional dendritic cells via a Zbtb46(+)Ly6D(+) intermediary stage


Lutz, K., Musumeci, A., Sie, C., Dursun, E., Winheim, E., Bagnoli, J., Ziegenhain, C., Rausch, L., Bergen, V., Luecken, M.D., Oostendorp, R.A.J., Schraml, B.U., Theis, F.J., Enard, W., Korn, T., Krug, A.B. (2022). Nat Commun 13, 3456.

DOI:10.1038/s41467-022-31054-4

Lymph node stromal cells support the maturation of pre-DCs into cDC-like cells via colony-stimulating factor 1


Wiechers, C., Pezoldt, J., Beckstette, M., Berner, J., Schraml, B.U., Huehn, J. (2022). Immunology.

DOI:10.1111/imm.13497

MCL1 as putative target in pancreatoblastoma


Reissig, T.M., Uhrig, S., Jost, P.J., Luchini, C., Vicentini, C., Liffers, S.T., Allgauer, M., Adsay, V., Scarpa, A., Lawlor, R.T., Frohling, S., Stenzinger, A., Kloppel, G., Schildhaus, H.U., Siveke, J.T. (2022). Virchows Arch.

DOI:10.1007/s00428-022-03349-w

Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer


Demel, U.M., Boger, M., Yousefian, S., Grunert, C., Zhang, L., Hotz, P.W., Gottschlich, A., Kose, H., Isaakidis, K., Vonficht, D., Grunschlager, F., Rohleder, E., Wagner, K., Donig, J., Igl, V., Brzezicha, B., Baumgartner, F., Habringer, S., Lober, J., Chapuy, B., Weidinger, C., Kobold, S., Haas, S., Busse, A.B., Muller, S., Wirth, M., Schick, M., Keller, U. (2022). J Clin Invest 132.

DOI:10.1172/JCI152383

Active Tumor-Targeting Nano-formulations Containing Simvastatin and Doxorubicin Inhibit Melanoma Growth and Angiogenesis


Negrea, G., Rauca, V.F., Meszaros, M.S., Patras, L., Luput, L., Licarete, E., Toma, V.A., Porfire, A., Muntean, D., Sesarman, A., Banciu, M. (2022). Front Pharmacol 13, 870347.

DOI:10.3389/fphar.2022.870347

Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation


Maisam Afzali, A., Stuve, L., Pfaller, M., Aly, L., Steiger, K., Knier, B., Korn, T. (2022). J Mol Med (Berl).

DOI:10.1007/s00109-022-02202-6