Publications



eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content.


Duan, H., Zhang, S., Zarai, Y., Öllinger, R., Wu, Y., Sun, L., Hu, C., He, Y., Tian, G., Rad, R., Kong, X., Cheng, Y., Tuller, T. & Wolf, D. A. (2023). Embo j, e112362.

DOI:10.15252/embj.2022112362

Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation.


Swietlik, J. J., Bärthel, S., Falcomatà, C., Fink, D., Sinha, A., Cheng, J., Ebner, S., Landgraf, P., Dieterich, D. C., Daub, H., Saur, D. & Meissner, F. (2023). Nat Commun, 14, 2642.

DOI:10.1038/s41467-023-38171-8

Elevated RIPK3 correlates with disease burden in myelofibrosis. v


Wagner, C. V., Keller, E. C., Fernandez-Hernandez, F. J., Shoumariyeh, K., Odinius, T. O., Buschhorn, L., Hauch, R. T., Suren, C., Hecker, J. S., Herhaus, P., Sandherr, M., Schmidt, B., Slotta-Huspenina, J., Bassermann, F., Höckendorf, U., Jilg, S., Branca, C., Vosberg, S. & Jost, P. J. (2023). Blood Adv, 7, 1219-1224.

DOI:10.1182/bloodadvances.2021006838

α-Gal present on both glycolipids and glycoproteins contributes to immune response in meat-allergic patients.


Chakrapani, N., Fischer, J., Swiontek, K., Codreanu-Morel, F., Hannachi, F., Morisset, M., Mugemana, C., Bulaev, D., Blank, S., Bindslev-Jensen, C., Biedermann, T., Ollert, M. & Hilger, C. (2022). J Allergy Clin Immunol, 150, 396-405.e311.

DOI:10.1016/j.jaci.2022.02.030

A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy


Stein-Thoeringer, C. K., Saini, N. Y., Zamir, E., Blumenberg, V., Schubert, M. L., Mor, U., Fante, M. A., Schmidt, S., Hayase, E., Hayase, T., Rohrbach, R., Chang, C. C., McDaniel, L., Flores, I., Gaiser, R., Edinger, M., Wolff, D., Heidenreich, M., Strati, P., Nair, R., Chihara, D., Fayad, L. E., Ahmed, S., Iyer, S. P., Steiner, R. E., Jain, P., Nastoupil, L. J., Westin, J., Arora, R., Wang, M. L., Turner, J., Menges, M., Hidalgo-Vargas, M., Reid, K., Dreger, P., Schmitt, A., Müller-Tidow, C., Locke, F. L., Davila, M. L., Champlin, R. E., Flowers, C. R., Shpall, E. J., Poeck, H., Neelapu, S. S., Schmitt, M., Subklewe, M., Jain, M. D., Jenq, R. R. & Elinav, E. (2023). Nat Med.

DOI:10.1038/s41591-023-02234-6

The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice.


Morrish, E., Wartewig, T., Kratzert, A., Rosenbaum, M., Steiger, K. & Ruland, J. (2022). Eur J Immunol, e2250147.

DOI:10.1002/eji.202250147

Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300


Hettler, F., Schreck, C., Marquez, S. R., Engleitner, T., Vilne, B., Landspersky, T., Weidner, H., Hausinger, R., Mishra, R., Oellinger, R., Rauner, M., Naumann, R., Peschel, C., Bassermann, F., Rad, R., Istvanffy, R. & Oostendorp, R. A. J. (2023). Haematologica, 108, 490-501.

DOI:10.3324/haematol.2022.280760

Small-molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy


Demel, U. M., Wirth, M., Yousefian, S., Zhang, L., Isaakidis, K., Donig, J., Boger, M., Singh, N., Kose, H., Haas, S., Muller, S., Schick, M. & Keller, U. (2023). Haematologica, 108, 555-567.

DOI:10.3324/haematol.2022.280995

CLEC12A Binds to Legionella pneumophila but Has No Impact on the Host's Antibacterial Response.


Klatt, A.-B., Diersing, C., Lippmann, J., Mayer-Lambertz, S., Stegmann, F., Fischer, S., Caesar, S., Fiocca Vernengo, F., Honzke, K., Hocke, A. C., Ruland, J., Witzenrath, M., Lepenies, B. & Opitz, B. (2023). International journal of molecular sciences, 24.

DOI:10.3390/ijms24043891

NASH and Hepatocellular Carcinoma: Immunology and Immunotherapy


Pinter, M., Pinato, D. J., Ramadori, P. & Heikenwalder, M. (2023). Clin Cancer Res, 29, 513-520.

DOI:10.1158/1078-0432.Ccr-21-1258