Publications



Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation.


Swietlik, J. J., Bärthel, S., Falcomatà, C., Fink, D., Sinha, A., Cheng, J., Ebner, S., Landgraf, P., Dieterich, D. C., Daub, H., Saur, D. & Meissner, F. (2023). Nat Commun, 14, 2642.

DOI:10.1038/s41467-023-38171-8

A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy


Stein-Thoeringer, C. K., Saini, N. Y., Zamir, E., Blumenberg, V., Schubert, M. L., Mor, U., Fante, M. A., Schmidt, S., Hayase, E., Hayase, T., Rohrbach, R., Chang, C. C., McDaniel, L., Flores, I., Gaiser, R., Edinger, M., Wolff, D., Heidenreich, M., Strati, P., Nair, R., Chihara, D., Fayad, L. E., Ahmed, S., Iyer, S. P., Steiner, R. E., Jain, P., Nastoupil, L. J., Westin, J., Arora, R., Wang, M. L., Turner, J., Menges, M., Hidalgo-Vargas, M., Reid, K., Dreger, P., Schmitt, A., Müller-Tidow, C., Locke, F. L., Davila, M. L., Champlin, R. E., Flowers, C. R., Shpall, E. J., Poeck, H., Neelapu, S. S., Schmitt, M., Subklewe, M., Jain, M. D., Jenq, R. R. & Elinav, E. (2023). Nat Med.

DOI:10.1038/s41591-023-02234-6

Small-molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy


Demel, U. M., Wirth, M., Yousefian, S., Zhang, L., Isaakidis, K., Donig, J., Boger, M., Singh, N., Kose, H., Haas, S., Muller, S., Schick, M. & Keller, U. (2023). Haematologica, 108, 555-567.

DOI:10.3324/haematol.2022.280995

NASH and Hepatocellular Carcinoma: Immunology and Immunotherapy


Pinter, M., Pinato, D. J., Ramadori, P. & Heikenwalder, M. (2023). Clin Cancer Res, 29, 513-520.

DOI:10.1158/1078-0432.Ccr-21-1258

Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.


Rosenberg, N., Van Haele, M., Lanton, T., Brashi, N., Bromberg, Z., Adler, H., Giladi, H., Peled, A., Goldenberg, D. S., Axelrod, J. H., Simerzin, A., Chai, C., Paldor, M., Markezana, A., Yaish, D., Shemulian, Z., Gross, D., Barnoy, S., Gefen, M., Amran, O., Claerhout, S., Fernandez-Vaquero, M., Garcia-Beccaria, M., Heide, D., Shoshkes-Carmel, M., Arras, D. S., Elgavish, S., Nevo, Y., Benyamini, H., Tirnitz-Parker, J. E. E., Sanchez, A., Herrera, B., Safadi, R., Kaestner, K. H., Rose-John, S., Roskams, T., Heikenwalder, M. & Galun, E. (2022). J. Hepatol., 77, 1631-1641.

DOI:10.1016/j.jhep.2022.07.029

Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status


Bader, J. M., Deigendesch, N., Misch, M., Mann, M., Koch, A. & Meissner, F. (2023). Cell Rep Med, 4, 100877.

DOI:10.1016/j.xcrm.2022.100877

Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues.


Probst, H. C., Stoitzner, P., Amon, L., Backer, R. A., Brand, A., Chen, J., Clausen, B. E., Dieckmann, S., Dudziak, D., Heger, L., Hodapp, K., Hornsteiner, F., Hovav, A. H., Jacobi, L., Ji, X., Kamenjarin, N., Lahl, K., Lahmar, I., Lakus, J., Lehmann, C. H. K., Ortner, D., Picard, M., Roberti, M. P., Rossnagel, L., Saba, Y., Schalla, C., Schlitzer, A., Schraml, B. U., Schütze, K., Seichter, A., Seré, K., Seretis, A., Sopper, S., Strandt, H., Sykora, M. M., Theobald, H., Tripp, C. H. & Zitvogel, L. (2022). Eur J Immunol. 0:1-78.

DOI:10.1002/eji.202249819

T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer.


Xue, B., von Heyking, K., Gassmann, H., Poorebrahim, M., Thiede, M., Schober, K., Mautner, J., Hauer, J., Ruland, J., Busch, D. H., Thiel, U. & Burdach, S. E. G. (2022). Cancers (Basel), 14.

DOI:10.3390/cancers14225485

The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma


Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J., Klaeger, S., Walzik, M., Öllinger, R., Engleitner, T., Wirth, M., Keller, U., Krönke, J., Rudelius, M., Kossatz, S., Rad, R., Kuster, B., Bassermann, F. (2022). EMBO J 41, e110871.

DOI:10.15252/embj.2022110871

Function and targeting of MALT1 paracaspase in cancer.


O'Neill, T. J., Tofaute, M. J. & Krappmann, D. (2023). Cancer Treat Rev, 117, 102568.

DOI:10.1016/j.ctrv.2023.102568