Publications



Ly6D(+)Siglec-H(+) precursors contribute to conventional dendritic cells via a Zbtb46(+)Ly6D(+) intermediary stage


Lutz, K., Musumeci, A., Sie, C., Dursun, E., Winheim, E., Bagnoli, J., Ziegenhain, C., Rausch, L., Bergen, V., Luecken, M.D., Oostendorp, R.A.J., Schraml, B.U., Theis, F.J., Enard, W., Korn, T., Krug, A.B. (2022). Nat Commun 13, 3456.

DOI:10.1038/s41467-022-31054-4

Ly6D(+)Siglec-H(+) precursors contribute to conventional dendritic cells via a Zbtb46(+)Ly6D(+) intermediary stage


Lutz, K., Musumeci, A., Sie, C., Dursun, E., Winheim, E., Bagnoli, J., Ziegenhain, C., Rausch, L., Bergen, V., Luecken, M.D., Oostendorp, R.A.J., Schraml, B.U., Theis, F.J., Enard, W., Korn, T., Krug, A.B. (2022). Nat Commun 13, 3456.

DOI:10.1038/s41467-022-31054-4

Lymph node stromal cells support the maturation of pre-DCs into cDC-like cells via colony-stimulating factor 1


Wiechers, C., Pezoldt, J., Beckstette, M., Berner, J., Schraml, B.U., Huehn, J. (2022). Immunology.

DOI:10.1111/imm.13497

MCL1 as putative target in pancreatoblastoma


Reissig, T.M., Uhrig, S., Jost, P.J., Luchini, C., Vicentini, C., Liffers, S.T., Allgauer, M., Adsay, V., Scarpa, A., Lawlor, R.T., Frohling, S., Stenzinger, A., Kloppel, G., Schildhaus, H.U., Siveke, J.T. (2022). Virchows Arch.

DOI:10.1007/s00428-022-03349-w

Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer


Demel, U.M., Boger, M., Yousefian, S., Grunert, C., Zhang, L., Hotz, P.W., Gottschlich, A., Kose, H., Isaakidis, K., Vonficht, D., Grunschlager, F., Rohleder, E., Wagner, K., Donig, J., Igl, V., Brzezicha, B., Baumgartner, F., Habringer, S., Lober, J., Chapuy, B., Weidinger, C., Kobold, S., Haas, S., Busse, A.B., Muller, S., Wirth, M., Schick, M., Keller, U. (2022). J Clin Invest 132.

DOI:10.1172/JCI152383

Active Tumor-Targeting Nano-formulations Containing Simvastatin and Doxorubicin Inhibit Melanoma Growth and Angiogenesis


Negrea, G., Rauca, V.F., Meszaros, M.S., Patras, L., Luput, L., Licarete, E., Toma, V.A., Porfire, A., Muntean, D., Sesarman, A., Banciu, M. (2022). Front Pharmacol 13, 870347.

DOI:10.3389/fphar.2022.870347

Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation


Maisam Afzali, A., Stuve, L., Pfaller, M., Aly, L., Steiger, K., Knier, B., Korn, T. (2022). J Mol Med (Berl).

DOI:10.1007/s00109-022-02202-6

Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression


Groll, T., Silva, M., Sarker, R.S.J., Tschurtschenthaler, M., Schnalzger, T., Mogler, C., Denk, D., Scholch, S., Schraml, B.U., Ruland, J., Rad, R., Saur, D., Weichert, W., Jesinghaus, M., Matiasek, K., Steiger, K. (2022). Cancers (Basel) 14.

DOI:10.3390/cancers14092248

Isolation of Neoantigen-Specific Human T Cell Receptors from Different Human and Murine Repertoires


Grunert, C., Willimsky, G., Peuker, C.A., Rhein, S., Hansmann, L., Blankenstein, T., Blanc, E., Beule, D., Keller, U., Pezzutto, A., Busse, A. (2022). Cancers (Basel) 14.

DOI:10.3390/cancers14071842

NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer


Doffo, J., Bamopoulos, S.A., Kose, H., Orben, F., Zang, C., Pons, M., den Dekker, A.T., Brouwer, R.W.W., Baluapuri, A., Habringer, S., Reichert, M., Illendula, A., Kramer, O.H., Schick, M., Wolf, E., van, I.W.F.J., Esposito, I., Keller, U., Schneider, G., Wirth, M. (2022). Proc Natl Acad Sci U S A 119.

DOI:10.1073/pnas.2105691119