Publications



Combining precision oncology and immunotherapy by targeting the MALT1 protease.


Mempel, T. R., Krappmann, D. (2022). J Immunother Cancer 10.
DOI:10.1136/jitc-2022-005442

The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma


Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J., Klaeger, S., Walzik, M., Öllinger, R., Engleitner, T., Wirth, M., Keller, U., Krönke, J., Rudelius, M., Kossatz, S., Rad, R., Kuster, B., Bassermann, F. (2022). EMBO J 41, e110871.

DOI:10.15252/embj.2022110871

A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.


Kreft, L., Schepers, A., Hils, M., Swiontek, K., Flatley, A., Janowski, R., Mirzaei, M. K., Dittmar, M., Chakrapani, N., Desai, M. S., Eyerich, S., Deng, L., Niessing, D., Fischer, K., Feederle, R., Blank, S., Schmidt-Weber, C. B., Hilger, C., Biedermann, T., Ohnmacht, C. (2022). Front Immunol 13, 958952.

DOI:10.3389/fimmu.2022.958952

Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection


Khatamzas, E., Antwerpen, M. H., Rehn, A., Graf, A., Hellmuth, J. C., Hollaus, A., Mohr, A. W., Gaitzsch, E., Weiglein, T., Georgi, E., Scherer, C., Stecher, S. S., Gruetzner, S., Blum, H., Krebs, S., Reischer, A., Leutbecher, A., Subklewe, M., Dick, A., Zange, S., Girl, P., Müller, K., Weigert, O., Hopfner, K. P., Stemmler, H. J., von Bergwelt-Baildon, M., Keppler, O. T., Wölfel, R., Muenchhoff, M., Moosmann, A. (2022). Nat Commun 13, 5586.

DOI:10.1038/s41467-022-32772-5

Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits


Peiseler, M., Schwabe, R., Hampe, J., Kubes, P., Heikenwälder, M., Tacke, F. (2022). J Hepatol 77, 1136-1160.

DOI:10.1016/j.jhep.2022.06.012

Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1


Jones, A. N., Graß, C., Meininger, I., Geerlof, A., Klostermann, M., Zarnack, K., Krappmann, D., Sattler, M. (2022). Sci Adv 8, eabp9153.

DOI:10.1126/sciadv.abp9153

Spinal Lesions as Clinical Manifestations of Plasma Cell Neoplasia.


Baumgart, L., Barz, M., Delbridge, C., Aftahy, A. K., Janssen, I. K., Jost, P. J., Ryang, Y. M., Meyer, B., Gempt, J. (2022). Curr Oncol 29, 6236-6244.

DOI:10.3390/curroncol29090490

Vascular Remodeling Is a Crucial Event in the Early Phase of Hepatocarcinogenesis in Rodent Models for Liver Tumorigenesis


Tulessin, M., Sarker, R.S.J., Griger, J., Leibing, T., Geraud, C., Weichert, W., Steiger, K., Mogler, C. (2022). Cells 11.

DOI:10.3390/cells11142129

pT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas-proposal for a new pT3a/pT3b subclassification


Foersch, S., Lang-Schwarz, C., Eckstein, M., Geppert, C., Schmitt, M., Konukiewitz, B., Groll, T., Schicktanz, F., Engel, J., Gleitsmann, M., Westhoff, C.C., Frickel, N., Litmeyer, A.S., Grass, A., Jank, P., Lange, S., Tschurtschenthaler, M., Wilhelm, D., Roth, W., Vieth, M., Denkert, C., Nagtegaal, I., Weichert, W., Jesinghaus, M. (2022). Br J Cancer.

DOI:10.1038/s41416-022-01889-1

Optimized CRISPR-Cas9-based Strategy for Complex Gene Targeting in Murine Embryonic Stem Cells for Germline Transmission


O'Neill, T.J., Krappmann, D., Gewies, A. (2022). Bio Protoc 12, e4423.

DOI:10.21769/BioProtoc.4423