Publications



USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling


Giebel, N., de Jaime-Soguero, A., Garcia Del Arco, A., Landry, J. J. M., Tietje, M., Villacorta, L., Benes, V., Fernandez-Saiz, V., Acebron, S. P. (2021). EMBO Rep 22, e51415.

DOI:10.15252/embr.202051415(link is external)

Tumor cell-intrinsic RIG-I signaling governs synergistic effects of immunogenic cancer therapies and checkpoint inhibitors in mice


Poeck, H., Wintges, A., Dahl, S., Bassermann, F., Haas, T., Heidegger, S. (2021). Eur J Immunol 51, 1531-1534.

DOI:10.1002/eji.202049158(link is external)

One concept does not fit all: the immune system in different forms of acute kidney injury


Anders, H. J., Wilkens, L., Schraml, B., Marschner, J. (2021). Nephrol Dial Transplant 36, 29-38.

DOI:10.1093/ndt/gfaa056(link is external)

Pre-digest of unprotected DNA by Benzonase improves the representation of living skin bacteria and efficiently depletes host DNA


Amar, Y., Lagkouvardos, I., Silva, R. L., Ishola, O. A., Foesel, B. U., Kublik, S., Scholer, A., Niedermeier, S., Bleuel, R., Zink, A., Neuhaus, K., Schloter, M., Biedermann, T., Koberle, M. (2021). Microbiome 9, 123.

DOI:10.1186/s40168-021-01067-0(link is external)

MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF


Wang, X., Ros, U., Agrawal, D., Keller, E. C., Slotta-Huspenina, J., Dill, V., Shen, B., Shi, R., Herold, T., Belka, C., Misra, R., Bassermann, F., Garcia-Saez, A. J., Jost, P. J. (2021). Cell Death Differ.

DOI:10.1038/s41418-021-00811-1(link is external)

Morphology Matters: A Critical Reappraisal of the Clinical Relevance of Morphologic Criteria From the 2019 WHO Classification in a Large Colorectal Cancer Cohort Comprising 1004 Cases


Jesinghaus, M., Schmitt, M., Lang, C., Reiser, M., Scheiter, A., Konukiewitz, B., Steiger, K., Silva, M., Tschurtschenthaler, M., Lange, S., Foersch, S., Becker, K. F., Saur, D., Friess, H., Halfter, K., Engel, J., Boxberg, M., Pfarr, N., Wilhelm, D., Weichert, W. (2021). Am J Surg Pathol 45, 969-978.

DOI:10.1097/PAS.0000000000001692(link is external)

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer


Sadras, T., Martin, M., Kume, K., Robinson, M. E., Saravanakumar, S., Lenz, G., Chen, Z., Song, J. Y., Siddiqi, T., Oksa, L., Knapp, A. M., Cutler, J., Cosgun, K. N., Klemm, L., Ecker, V., Winchester, J., Ghergus, D., Soulas-Sprauel, P., Kiefer, F., Heisterkamp, N., Pandey, A., Ngo, V., Wang, L., Jumaa, H., Buchner, M., Ruland, J., Chan, W. C., Meffre, E., Martin, T., Muschen, M. (2021). Mol Cell 81, 2094-2111 e2099.

DOI:10.1016/j.molcel.2021.03.043(link is external)

Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia


Ecker, V., Stumpf, M., Brandmeier, L., Neumayer, T., Pfeuffer, L., Engleitner, T., Ringshausen, I., Nelson, N., Jucker, M., Wanninger, S., Zenz, T., Wendtner, C., Manske, K., Steiger, K., Rad, R., Muschen, M., Ruland, J., Buchner, M. (2021). Nat Commun 12, 3526.

DOI:10.1038/s41467-021-23752-2(link is external)

Loss of direct adrenergic innervation after peripheral nerve injury causes lymph node expansion through IFN-gamma


Chen, C. S., Weber, J., Holtkamp, S. J., Ince, L. M., de Juan, A., Wang, C., Lutes, L., Barnoud, C., Kizil, B., Hergenhan, S. M., Salvermoser, J., Lasch, M., Deindl, E., Schraml, B., Baumjohann, D., Scheiermann, C. (2021). J Exp Med 218.

DOI:10.1084/jem.20202377(link is external)

Molecular mechanisms of nonself nucleic acid recognition by the innate immune system


de Oliveira Mann, C. C.  and Hornung, V. (2021). Eur J Immunol 51, 1897-1910.

DOI:10.1002/eji.202049116(link is external)