Publications



The fusion oncogene VAV1-MYO1F triggers aberrant T-cell receptor signaling in vivo and drives peripheral T-cell lymphoma in mice.


Morrish, E., Wartewig, T., Kratzert, A., Rosenbaum, M., Steiger, K. & Ruland, J. (2022). Eur J Immunol, e2250147.

DOI:10.1002/eji.202250147

The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma


Paulmann, C., Spallek, R., Karpiuk, O., Heider, M., Schäffer, I., Zecha, J., Klaeger, S., Walzik, M., Öllinger, R., Engleitner, T., Wirth, M., Keller, U., Krönke, J., Rudelius, M., Kossatz, S., Rad, R., Kuster, B., Bassermann, F. (2022). EMBO J 41, e110871.

DOI:10.15252/embj.2022110871

Function and targeting of MALT1 paracaspase in cancer.


O'Neill, T. J., Tofaute, M. J. & Krappmann, D. (2023). Cancer Treat Rev, 117, 102568.

DOI:10.1016/j.ctrv.2023.102568

α-Gal present on both glycolipids and glycoproteins contributes to immune response in meat-allergic patients


Chakrapani, N., Fischer, J., Swiontek, K., Codreanu-Morel, F., Hannachi, F., Morisset, M., Mugemana, C., Bulaev, D., Blank, S., Bindslev-Jensen, C., Biedermann, T., Ollert, M. & Hilger, C. (2022). Allergy Clin Immunol, 150, 396-405.e311.

DOI:10.1016/j.jaci.2022.02.030

Combining precision oncology and immunotherapy by targeting the MALT1 protease.


Mempel, T. R., Krappmann, D. (2022). J Immunother Cancer 10.
DOI:10.1136/jitc-2022-005442

A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.


Kreft, L., Schepers, A., Hils, M., Swiontek, K., Flatley, A., Janowski, R., Mirzaei, M. K., Dittmar, M., Chakrapani, N., Desai, M. S., Eyerich, S., Deng, L., Niessing, D., Fischer, K., Feederle, R., Blank, S., Schmidt-Weber, C. B., Hilger, C., Biedermann, T., Ohnmacht, C. (2022). Front Immunol 13, 958952.

DOI:10.3389/fimmu.2022.958952

Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection


Khatamzas, E., Antwerpen, M. H., Rehn, A., Graf, A., Hellmuth, J. C., Hollaus, A., Mohr, A. W., Gaitzsch, E., Weiglein, T., Georgi, E., Scherer, C., Stecher, S. S., Gruetzner, S., Blum, H., Krebs, S., Reischer, A., Leutbecher, A., Subklewe, M., Dick, A., Zange, S., Girl, P., Müller, K., Weigert, O., Hopfner, K. P., Stemmler, H. J., von Bergwelt-Baildon, M., Keppler, O. T., Wölfel, R., Muenchhoff, M., Moosmann, A. (2022). Nat Commun 13, 5586.

DOI:10.1038/s41467-022-32772-5

Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits


Peiseler, M., Schwabe, R., Hampe, J., Kubes, P., Heikenwälder, M., Tacke, F. (2022). J Hepatol 77, 1136-1160.

DOI:10.1016/j.jhep.2022.06.012

Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1


Jones, A. N., Graß, C., Meininger, I., Geerlof, A., Klostermann, M., Zarnack, K., Krappmann, D., Sattler, M. (2022). Sci Adv 8, eabp9153.

DOI:10.1126/sciadv.abp9153

Spinal Lesions as Clinical Manifestations of Plasma Cell Neoplasia.


Baumgart, L., Barz, M., Delbridge, C., Aftahy, A. K., Janssen, I. K., Jost, P. J., Ryang, Y. M., Meyer, B., Gempt, J. (2022). Curr Oncol 29, 6236-6244.

DOI:10.3390/curroncol29090490