Publications



RIG-I activation is critical for responsiveness to checkpoint blockade


Heidegger, S., Wintges, A., Stritzke, F., Bek, S., Steiger, K., Koenig, P. A., Gottert, S., Engleitner, T., Ollinger, R., Nedelko, T., Fischer, J. C., Makarov, V., Winter, C., Rad, R., van den Brink, M. R. M., Ruland, J., Bassermann, F., Chan, T. A., Haas, T., Poeck, H. (2019). Sci Immunol 4.

DOI:10.1126/sciimmunol.aau8943(link is external)

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells


Gehring, T., Erdmann, T., Rahm, M., Grass, C., Flatley, A., O'Neill, T. J., Woods, S., Meininger, I., Karayel, O., Kutzner, K., Grau, M., Shinohara, H., Lammens, K., Feederle, R., Hauck, S. M., Lenz, G., Krappmann, D. (2019). Cell Reports 29, 873-888 e10.

DOI:10.1016/j.celrep.2019.09.040(link is external)

Type I interferon signaling before hematopoietic stem cell transplantation lowers donor T cell activation via reduced allogenicity of recipient cells


Fischer, J. C., Bscheider, M., Gottert, S., Thiele Orberg, E., Combs, S. E., Bassermann, F., Heidegger, S., Haas, T., Poeck, H. (2019). Sci Rep 9, 14955.

DOI:10.1038/s41598-019-51431-2(link is external)

Engineering CRISPR mouse models of cancer


Weber, J. and Rad, R. (2019). Curr Opin Genet Dev 54, 88-96.

DOI:10.1016/j.gde.2019.04.001(link is external)

Towards quantitative imaging biomarkers of tumor dissemination: A multi-scale parametric modeling of multiple myeloma


Piraud, M., Wennmann, M., Kintzele, L., Hillengass, J., Keller, U., Langs, G., Weber, M.A., Menze, B.H. (2019). Med Image Anal 57, 214-225.

DOI: 10.1016/j.media.2019.07.001(link is external)

RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade


Heidegger, S., Kreppel, D., Bscheider, M., Stritzke, F., Nedelko, T., Wintges, A., Bek, S., Fischer, J.C., Graalmann, T., Kalinke, U., Bassermann, F., Haas, T., Poeck, H. (2019). EBioMedicine 41, 146-155.

DOI: 10.1016/j.ebiom.2019.02.056(link is external)

Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology


Palit, S., Heuser, C., de Almeida, G.P., Theis, F.J., Zielinski, C.E. (2019). Front Immunol 10, 1515.

DOI: 10.3389/fimmu.2019.01515(link is external)

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection


Alfei, F., Kanev, K., Hofmann, M., Wu, M., Ghoneim, H.E., Roelli, P., Utzschneider, D.T., von Hoesslin, M., Cullen, J.G., Fan, Y., Eisenberg, V., Wohlleber, D., Steiger, K., Merkler, D., Delorenzi, M., Knolle, P.A., Cohen, C.J., Thimme, R., Youngblood, B., Zehn, D. (2019). Nature 571, 265-269.

DOI: 10.1038/s41586-019-1326-9(link is external)

Shaping the diversity of Th2 cell responses in epithelial tissues and its potential for allergy treatment


Matthias, J. and Zielinski, C.E. (2019). Eur J Immunol 49, 1321-1333.

DOI: 10.1002/eji.201848011(link is external)

From NASH to HCC: current concepts and future challenges


Anstee, Q.M., Reeves, H.L., Kotsiliti, E., Govaere, O., Heikenwalder, M. (2019). Nat Rev Gastroenterol Hepatol 16, 411-428.

DOI: 10.1038/s41575-019-0145-7(link is external)