Publications



Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells


Rosenbaum, M., Gewies, A., Pechloff, K., Heuser, C., Engleitner, T., Gehring, T., Hartjes, L., Krebs, S., Krappmann, D., Kriegsmann, M., Weichert, W., Rad, R., Kurts, C., Ruland, J. (2019). Nat Commun 10, 2352.

DOI: 10.1038/s41467-019-10203-2(link is external)

SDF1α-induced chemotaxis of JAK2-V617F positive cells is dependent on Bruton's Tyrosine Kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA


Nimmagadda, S.C., Frey, S., Müller, P., Wolleschak, D., Weinert, S., Keller, U., Edelmann, B., Fischer, T. (2019). Haematologica 104, e288-e292.

DOI: 10.3324/haematol.2018.20192(link is external)

PD-1 Tumor Suppressor Signaling in T Cell Lymphomas


Wartewig, T. and Ruland, J. (2019). Trends Immunol 40, 403-414.

DOI: 10.1016/j.it.2019.03.005(link is external)

Side effects of CXC-chemokine receptor 4 - directed Endoradiotherapy with Pentixather prior to Hematopoietic Stem Cell Transplantation


Maurer, S., Herhaus, P., Lippenmeyer, R., Hänscheid, H., Kircher, M., Schirbel, A., Maurer, H.C., Buck, A.K., Wester, H.J., Einsele, H., Grigoleit, G.U., Keller, U., Lapa C. (2019). J Nucl Med 60, 1339-1405.

DOI: 10.2967/jnumed.118.223420(link is external)

CARD9 Signaling in Intestinal Immune Homeostasis and Oncogenesis


Hartjes, L. and Ruland, J. (2019). Front Immunol 10, 419.

DOI: 10.3389/fimmu.2019.00419(link is external)

XIAP deficiency in hematopoietic recipient cells drives donor T-cell activation and GvHD in mice


Muller, N., Fischer, J.C., Yabal, M., Haas, T., Poeck, H., Jost, P.J. (2019). Eur J Immunol 49, 504-507.

DOI: 10.1002/eji.201847818(link is external)

DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer


Paludan, S.R., Reinert, L.S., Hornung, V. (2019). Nat Rev Immunol 19, 141-153.

DOI: 10.1038/s41577-018-0117-0(link is external)

Targeting intrinsic RIG-I signaling turns melanoma cells into type I interferon-releasing cellular antitumor vaccines


Bek, S., Stritzke, F., Wintges A., Nedelko, T., Böhmer, D.F.R.,  Fischer, J.C., Haas, T., Poeck, H., Heidegger, S. (2019). OncoImmunology 8, e1570779.

DOI: 10.1080/2162402X.2019.1570779(link is external)

Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis


Coleman, O.I., Lobner, E.M., Bierwirth, S., Sorbie, A., Waldschmitt, N., Rath, E., Berger, E., Lagkouvardos, I., Clavel, T., McCoy, K.D., Weber, A., Heikenwalder, M., Janssen, K.P., Haller, D. (2018). Gastroenterology 155, 1539-1552 e1512.

DOI: 10.1053/j.gastro.2018.07.028(link is external)

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes


Kasper, L., Konig, A., Koenig, P.A., Gresnigt, M.S., Westman, J., Drummond, R.A., Lionakis, M.S., Gross, O., Ruland, J., Naglik, J.R., and Hube, B. (2018). Nat Commun 9, 4260.

DOI: 10.1038/s41467-018-06607-1