Publications



The Unsolved Puzzle of c-Rel in B Cell Lymphoma


Kober-Hasslacher, M. and Schmidt-Supprian, M. (2019). Cancers (Basel) 11.

DOI:10.3390/cancers11070941(link is external)

Activated gp130 signaling selectively targets B cell differentiation to induce mature lymphoma and plasmacytoma


Scherger, A.K., Al-Maarri, M., Maurer, H.C., Schick, M., Maurer, S., Ollinger, R., Gonzalez-Menendez, I., Martella, M., Thaler, M., Pechloff, K., Steiger, K., Sander, S., Ruland, J., Rad, R., Quintanilla-Martinez, L., Wunderlich, F.T., Rose-John, S., Keller, U. (2019). JCI Insight 4.

DOI: 10.1172/jci.insight.128435(link is external)

Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment


Matthias, J., Maul, J., Noster, R., Meinl, H., Chao, Y.Y., Gerstenberg, H., Jeschke, F., Gasparoni, G., Welle, A., Walter, J., Nordstrom, K., Eberhardt, K., Renisch, D., Donakonda, S., Knolle, P., Soll, D., Grabbe, S., Garzorz-Stark, N., Eyerich, K., Biedermann, T., Baumjohann, D., Zielinski, C.E. (2019). Sci Transl Med 11.

DOI: 10.1126/scitranslmed.aau0683(link is external)

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice


Weber, J., de la Rosa, J., Grove, C.S., Schick, M., Rad, L., Baranov, O., Strong, A., Pfaus, A., Friedrich, M.J., Engleitner, T., Lersch, R., Ollinger, R., Grau, M., Menendez, I.G., Martella, M., Kohlhofer, U., Banerjee, R., Turchaninova, M.A., Scherger, A., Hoffman, G.J., Hess, J., Kuhn, L.B., Ammon, T., Kim, J., Schneider, G., Unger, K., Zimber-Strobl, U., Heikenwalder, M., Schmidt-Supprian, M., Yang, F., Saur, D., Liu, P., Steiger, K., Chudakov, D.M., Lenz, G., Quintanilla-Martinez, L., Keller, U., Vassiliou, G.S., Cadinanos, J., Bradley, A., Rad, R. (2019). Nat Commun 10, 1415.

DOI: 10.1038/s41467-019-09180-3(link is external)

Deciphering the universe of genetic context-dependencies using mouse models of cancer


Falcomatà, C., Barthel, S., Schneider, G., Saur, D., Veltkamp, C. (2019). Curr Opin Genet Dev 54, 97-104.

DOI: 10.1016/j.gde.2019.04.002(link is external)

Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention


O'Connor, T., Zhou, X., Kosla, J., Adili, A., Garcia Beccaria, M., Kotsiliti, E., Pfister, D., Johlke, A. L., Sinha, A., Sankowski, R., Schick, M., Lewis, R., Dokalis, N., Seubert, B., Hochst, B., Inverso, D., Heide, D., Zhang, W., Weihrich, P., Manske, K., Wohlleber, D., Anton, M., Hoellein, A., Seleznik, G., Bremer, J., Bleul, S., Augustin, H. G., Scherer, F., Koedel, U., Weber, A., Protzer, U., Forster, R., Wirth, T., Aguzzi, A., Meissner, F., Prinz, M., Baumann, B., Hopken, U. E., Knolle, P. A., von Baumgarten, L., Keller, U., Heikenwalder, M. (2019). Cancer Cell 36, 250-267 e9.

DOI:10.1016/j.ccell.2019.08.001(link is external)

Colon Cancer: Epithelial Notch Signaling Recruits Neutrophils to Drive Metastasis.


Ruland, J. (2019). Cancer Cell 36, 213-214.

DOI:10.1016/j.ccell.2019.08.010(link is external)

RIG-I activation is critical for responsiveness to checkpoint blockade


Heidegger, S., Wintges, A., Stritzke, F., Bek, S., Steiger, K., Koenig, P. A., Gottert, S., Engleitner, T., Ollinger, R., Nedelko, T., Fischer, J. C., Makarov, V., Winter, C., Rad, R., van den Brink, M. R. M., Ruland, J., Bassermann, F., Chan, T. A., Haas, T., Poeck, H. (2019). Sci Immunol 4.

DOI:10.1126/sciimmunol.aau8943(link is external)

MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells


Gehring, T., Erdmann, T., Rahm, M., Grass, C., Flatley, A., O'Neill, T. J., Woods, S., Meininger, I., Karayel, O., Kutzner, K., Grau, M., Shinohara, H., Lammens, K., Feederle, R., Hauck, S. M., Lenz, G., Krappmann, D. (2019). Cell Reports 29, 873-888 e10.

DOI:10.1016/j.celrep.2019.09.040(link is external)

Type I interferon signaling before hematopoietic stem cell transplantation lowers donor T cell activation via reduced allogenicity of recipient cells


Fischer, J. C., Bscheider, M., Gottert, S., Thiele Orberg, E., Combs, S. E., Bassermann, F., Heidegger, S., Haas, T., Poeck, H. (2019). Sci Rep 9, 14955.

DOI:10.1038/s41598-019-51431-2(link is external)