Publications



Engineering CRISPR mouse models of cancer


Weber, J. and Rad, R. (2019). Curr Opin Genet Dev 54, 88-96.

DOI:10.1016/j.gde.2019.04.001(link is external)

Towards quantitative imaging biomarkers of tumor dissemination: A multi-scale parametric modeling of multiple myeloma


Piraud, M., Wennmann, M., Kintzele, L., Hillengass, J., Keller, U., Langs, G., Weber, M.A., Menze, B.H. (2019). Med Image Anal 57, 214-225.

DOI: 10.1016/j.media.2019.07.001(link is external)

RIG-I activating immunostimulatory RNA boosts the efficacy of anticancer vaccines and synergizes with immune checkpoint blockade


Heidegger, S., Kreppel, D., Bscheider, M., Stritzke, F., Nedelko, T., Wintges, A., Bek, S., Fischer, J.C., Graalmann, T., Kalinke, U., Bassermann, F., Haas, T., Poeck, H. (2019). EBioMedicine 41, 146-155.

DOI: 10.1016/j.ebiom.2019.02.056(link is external)

Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology


Palit, S., Heuser, C., de Almeida, G.P., Theis, F.J., Zielinski, C.E. (2019). Front Immunol 10, 1515.

DOI: 10.3389/fimmu.2019.01515(link is external)

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection


Alfei, F., Kanev, K., Hofmann, M., Wu, M., Ghoneim, H.E., Roelli, P., Utzschneider, D.T., von Hoesslin, M., Cullen, J.G., Fan, Y., Eisenberg, V., Wohlleber, D., Steiger, K., Merkler, D., Delorenzi, M., Knolle, P.A., Cohen, C.J., Thimme, R., Youngblood, B., Zehn, D. (2019). Nature 571, 265-269.

DOI: 10.1038/s41586-019-1326-9(link is external)

Shaping the diversity of Th2 cell responses in epithelial tissues and its potential for allergy treatment


Matthias, J. and Zielinski, C.E. (2019). Eur J Immunol 49, 1321-1333.

DOI: 10.1002/eji.201848011(link is external)

From NASH to HCC: current concepts and future challenges


Anstee, Q.M., Reeves, H.L., Kotsiliti, E., Govaere, O., Heikenwalder, M. (2019). Nat Rev Gastroenterol Hepatol 16, 411-428.

DOI: 10.1038/s41575-019-0145-7(link is external)

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells


Rosenbaum, M., Gewies, A., Pechloff, K., Heuser, C., Engleitner, T., Gehring, T., Hartjes, L., Krebs, S., Krappmann, D., Kriegsmann, M., Weichert, W., Rad, R., Kurts, C., Ruland, J. (2019). Nat Commun 10, 2352.

DOI: 10.1038/s41467-019-10203-2(link is external)

SDF1α-induced chemotaxis of JAK2-V617F positive cells is dependent on Bruton's Tyrosine Kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA


Nimmagadda, S.C., Frey, S., Müller, P., Wolleschak, D., Weinert, S., Keller, U., Edelmann, B., Fischer, T. (2019). Haematologica 104, e288-e292.

DOI: 10.3324/haematol.2018.20192(link is external)

PD-1 Tumor Suppressor Signaling in T Cell Lymphomas


Wartewig, T. and Ruland, J. (2019). Trends Immunol 40, 403-414.

DOI: 10.1016/j.it.2019.03.005(link is external)